簡(jiǎn)要描述:SHA 68,CAS:24211-36-7
SHA 68,CAS:24211-36-7
Selective neuropeptide S receptor (NPSR) antagonist (IC50 values are 22.0 and 23.8 nM for human NPSR Asn107 and Ile107 variants respectively). Displays no activity against a range of 14 GPCRs, including vasopressin and oxytocin receptors.
SHA 68 is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
M. Wt | 445.49 |
Formula | C26H24FN3O3 |
Storage | Store at +4°C |
Purity | ≥98% (HPLC) |
CAS Number | 847553-89-3 |
PubChem ID | 11374217 |
InChI Key | SFRQIPRTNYHJHP-UHFFFAOYSA-N |
Smiles | O=C(NCC4=CC=C(F)C=C4)N1CC2N(C(OC(C5=CC=CC=C5)2C3=CC=CC=C3)=O)CC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 44.55 | 100 | |
ethanol | 44.55 | 100 |